Optical coherence tomographic angiography detects retinal vascular changes associated with pituitary adenoma

Ping Wei; Julie Falardeau; Aiyin Chen; Jie Wang; Liang Liu; Yali Jia; David Huang

doi:10.1016/j.ajoc.2022.101711

Optical coherence tomographic angiography detects retinal vascular changes associated with pituitary adenoma

Am J Ophthalmol Case Rep. 2022 Sep 15:28:101711. doi: 10.1016/j.ajoc.2022.101711. eCollection 2022 Dec.

Authors

Ping Wei¹, Julie Falardeau¹, Aiyin Chen¹, Jie Wang¹, Liang Liu¹, Yali Jia¹, David Huang¹

Affiliation

¹ Casey Eye Institute and Department of Ophthalmology, Oregon Health and Science University, Portland, OR, USA.

Abstract

Purpose: To report the distinct pattern of retinal perfusion loss captured on optical coherence tomographic angiography (OCTA) in a case of compressive optic neuropathy associated with pituitary adenoma.

Observations: A 51-year-old male had bitemporal hemianopia caused by a pituitary adenoma that compressed the optic chiasm. OCTA scans in both eyes showed peripapillary nerve fiber layer plexus defects in the nasal hemispheres and papillomacular corridors. On macular scans, the ganglion cell layer plexus showed papillomacular defects. The perfusion defects corresponded with thinning on structural OCT measurement and loss of sensitivity on visual field tests.

Conclusions and importance: Chiasm compression produces a characteristic pattern of perfusion loss that can be recognized OCTA. This knowledge may be useful in the diagnosis and classification of optic neuropathies.

Keywords: Bitemporal hemianopia; OCT angiography; Pituitary adenoma.

Publication types

Case Reports