Evaluation of Lymphocyte-to-Monocyte Ratio and Mean Platelet Volume-to-Platelet Ratio in Rhegmatogenous Retinal Detachment

Xuan Xiao; Jiayi Song; Lin Ye; Wen Zuo; Hongxia Yang; Changzheng Chen; Hongmei Zheng; Ting Chen

doi:10.1155/2022/9127745

Evaluation of Lymphocyte-to-Monocyte Ratio and Mean Platelet Volume-to-Platelet Ratio in Rhegmatogenous Retinal Detachment

J Ophthalmol. 2022 Sep 16:2022:9127745. doi: 10.1155/2022/9127745. eCollection 2022.

Authors

Xuan Xiao¹, Jiayi Song¹, Lin Ye², Wen Zuo¹, Hongxia Yang¹, Changzheng Chen¹, Hongmei Zheng¹, Ting Chen¹

Affiliations

¹ Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
² Department of Eye Plastic and Lacrimal Diseases, Shenzhen Eye Hospital, Shenzhen, China.

Abstract

Purpose: To assess the predictive value of inflammatory blood biomarkers in rhegmatogenous retinal detachment (RRD) patients and its correlation with proliferative retinopathy (PVR) grade.

Methods: 82 RRD patients and 1 : 1 age- and gender-randomly matched cataract patients as the control group were included. The clinical features and laboratory parameters of all participants were collected and recorded, and the comprehensive index of inflammatory blood and its correlation with PVR were calculated.

Results: Monocytes and monocyte-to-high-density lipoprotein ratio (MHR) were significantly lower (P=0.005, P=0.044), while mean platelet volume (MPV), lymphocyte-to-monocyte ratio (LMR), and MPV-to-platelet ratio (MPR) were significantly higher in RRD patients as compared with the control group (P=0.013, P=0.019, P=0.037). LMR and MPR might be the predictors of RRD. The receiver operating characteristics analysis showed that the values of MPV, LMR, and MPR in RRD patients were 0.612, 0.606, and 0.594, respectively. PVR grade was not associated with inflammatory blood biomarkers.

Conclusion: The increase in MPV, LMR, and MPR were associated with increased odds of RRD. LMR and MPR may be useful as inexpensive and effortless biomarkers for assessing the occurrence of RRD.