Ketogenic diets in healthy dogs induce gut and serum metabolome changes suggestive of anti-tumourigenic effects: A model for human ketotherapy trials
Clin Transl Med
.
2022 Sep;12(9):e1047.
doi: 10.1002/ctm2.1047.
Authors
Karin Allenspach
1
,
Dana C Borcherding
2
,
Chelsea A Iennarella-Servantez
2
3
,
Allison P Mosichuk
1
,
Todd Atherly
1
,
Dipak Kumar Sahoo
2
,
Aarti Kathrani
3
,
Jan S Suchodolski
4
,
Agnes Bourgois-Mochel
1
,
Mariana Rossoni Serao
5
,
Nick V Serao
5
,
Auriel Willette
6
,
Beatriz Agulla Perez
1
,
Vojtech Gabriel
1
,
Sichao Mao
1
,
Logan Kilburn
5
,
Viet Dang
7
,
David Borts
7
,
Luciana L Almada
8
,
Martin E Fernandez-Zapico
8
,
Gregory J Phillips
9
,
Albert E Jergens
1
,
Jonathan P Mochel
2
Affiliations
1
Departments, of Veterinary Clinical Sciences, Iowa State University College of Veterinary Medicine, Ames, Iowa, USA.
2
Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Ames, Iowa, USA.
3
Royal Veterinary College, University of London, London, UK.
4
Gastrointestinal Laboratory, Texas A&M University, College of Veterinary Medicine & Biomedical Sciences, College Station, Texas, USA.
5
Department of Animal Science, Iowa State University, Ames, Iowa, USA.
6
Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.
7
Veterinary Diagnostics Laboratory, Iowa State University, Ames, Iowa, USA.
8
Schulze Center for Novel Therapeutics, Division of Oncology Research, Mayo Clinic, Rochester, Minnesota, USA.
9
Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA.
PMID:
36149786
PMCID:
PMC9506423
DOI:
10.1002/ctm2.1047
No abstract available
Publication types
Letter
Research Support, Non-U.S. Gov't
MeSH terms
Animals
Diet, Ketogenic*
Dogs
Gastrointestinal Microbiome*
Humans
Metabolome