Enhanced permeability and retention effect-focused tumor-targeted nanomedicines: latest trends, obstacles and future perspective

Saurabh Shekhar; Mahima Chauhan; Sonali; Bhavna Yadav; Rohit Dutt; Liandong Hu; Madaswamy S Muthu; Rahul Pratap Singh

doi:10.2217/nnm-2022-0065

Enhanced permeability and retention effect-focused tumor-targeted nanomedicines: latest trends, obstacles and future perspective

Nanomedicine (Lond). 2022 Aug;17(18):1213-1216. doi: 10.2217/nnm-2022-0065. Epub 2022 Sep 22.

Authors

Saurabh Shekhar¹, Mahima Chauhan¹, Sonali², Bhavna Yadav¹, Rohit Dutt¹, Liandong Hu³, Madaswamy S Muthu⁴, Rahul Pratap Singh¹

Affiliations

¹ Department of Pharmacy, School of Medical and Allied Sciences, GD Goenka University, Gurugram, 122103, India.
² Guru Teg Bahadur Hospital, GTB Enclave, Dilshad Garden, New Delhi, Delhi, 110095, India.
³ College of Quality and Technical Supervision and Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China.
⁴ Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi, 221005, India.

PMID: 36136592
DOI: 10.2217/nnm-2022-0065

No abstract available

Keywords: cancer nanomedicines; cancer/oncology; controlled drug release; enhanced permeability and retention effect; factors affecting EPR effect; nanoparticle toxicity; targeted cancer therapy.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Agents* / therapeutic use
Drug Delivery Systems
Humans
Nanomedicine
Nanoparticles*
Neoplasms* / drug therapy
Permeability

Substances

Antineoplastic Agents