Porphyrin covalent organic nanodisks synthesized using acid-assisted exfoliation for improved bactericidal efficacy

Xinxi Li; Hajime Shigemitsu; Tomoyo Goto; Toshiyuki Kida; Tohru Sekino; Mamoru Fujitsuka; Yasuko Osakada

doi:10.1039/d2na00318j

Porphyrin covalent organic nanodisks synthesized using acid-assisted exfoliation for improved bactericidal efficacy

Nanoscale Adv. 2022 Jun 16;4(14):2992-2995. doi: 10.1039/d2na00318j. eCollection 2022 Jul 15.

Authors

Xinxi Li¹, Hajime Shigemitsu², Tomoyo Goto^{1

3}, Toshiyuki Kida², Tohru Sekino¹, Mamoru Fujitsuka^{1

4}, Yasuko Osakada^{1

3

4}

Affiliations

¹ SANKEN (The Institute of Scientific and Industrial Research), Osaka University Mihogaoka 8-1 Ibaraki Osaka 567-0047 Japan yosakada@sanken.osaka-u.ac.jp fuji@sanken.osaka-u.ac.jp.
² Department of Applied Chemistry, Graduate School of Engineering, Osaka University 2-1 Yamadaoka Suita 565-0871 Japan.
³ Institute for Advanced Co-Creation Studies, Osaka University 1-1 Yamadagaoka Suita Osaka 565-0871 Japan.
⁴ Innovative Catalysis Science Division, Institute for Open and Transdisciplinary Research Initiatives (ICS-OTRI) Suita Osaka 565-0871 Japan.

Abstract

Porphyrin covalent organic nanodisks (CONs) were synthesized by exfoliating covalent organic frameworks (COFs) in acidic aqueous solutions at pH 4. The synthesized CONs showed remarkable bactericidal activity against Escherichia coli owing to enhanced generation of singlet oxygen upon visible light irradiation.