Estetrol is not a SERM but a NEST and has a specific safety profile on coagulation

Affiliations

• ¹ University of Namur, Faculty of Medicine, Department of Pharmacy, Namur Research Institute for Life Sciences (NARILIS), Clinical Pharmacology Research Group, Namur, Belgium; Qualiblood sa, Namur, Belgium. Electronic address: jonathan.douxfils@unamur.be.
• ² University of Namur, Faculty of Medicine, Department of Pharmacy, Namur Research Institute for Life Sciences (NARILIS), Clinical Pharmacology Research Group, Namur, Belgium; Qualiblood sa, Namur, Belgium.
• ³ Department of Obstetrics and Gynecology, University of Liège, Belgium.
• ⁴ Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
• ⁵ Estetra SRL, An affiliate's Company of Mithra Pharmaceuticals, Liège, Belgium; University of Liège, Liège, Belgium.