Archaea inhabit a wide variety of habitats and are well-placed to provide insights into the origins of eukaryotes. In this primer, we examine the available model archaeal genetic systems. We consider the limitations and barriers involved in genetically modifying different archaeal species, the techniques and breakthroughs that have contributed to their tractability, and potential areas for future development.
Keywords: Genetics; Halophiles; Methanogens; Sulfolobales; Thermococcales.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.