Optic cupping secondary to periventricular leukomalacia: A potential mimic for normal pressure glaucoma

Ahmed H El Beltagi; Nour Barakat; Loai Aker; Laith Abandeh; Ahmed Own; Mohamed Abdelhady; Hassan Aboughalia

doi:10.1016/j.radcr.2022.07.106

Optic cupping secondary to periventricular leukomalacia: A potential mimic for normal pressure glaucoma

Radiol Case Rep. 2022 Sep 11;17(11):4264-4267. doi: 10.1016/j.radcr.2022.07.106. eCollection 2022 Nov.

Authors

Ahmed H El Beltagi¹, Nour Barakat², Loai Aker³, Laith Abandeh⁴, Ahmed Own⁵, Mohamed Abdelhady⁵, Hassan Aboughalia⁶

Affiliations

¹ Neuroradiology Section, Neuroscience Institute, Hamad Medical Corporation, Weill Cornell Medicine, Doha, Qatar.
² Ophthalmology Department, Hamad Medical Corporation, Doha, Qatar.
³ Department of Clinical Imaging, Hamad Medical Corporation, P.O box 3050, Doha, Qatar.
⁴ Department of Radiology, University of Washington, Seattle, WA, USA.
⁵ Neuroradiology Section, Neuroscience Institute, Hamad Medical Corporation, Doha, Qatar.
⁶ Radiology Department, Seattle Children's Hospital, University of Washington Medical Center, Seattle, WA, USA.

Abstract

We herein present a case of periventricular leukomalacia (PVL) with secondary optic pathway denervation atrophy, which was initially labeled as normal tension glaucoma. However, given the discordant clinical and ophthalmologic findings, brain magnetic resonance imaging was requested which proved PVL to be the underlying process to the patient's decreased visual acuity. In addition to presenting the ophthalmologic findings, we are emphasizing the pivotal role of neuroimaging in ruling out central causes of optic atrophy/hypoplasia and making this clinical distinction by demonstrating optic pathway atrophy associated with PVL.

Keywords: Normal pressure glaucoma; Optic disk; Periventricular leukomalacia.

Publication types

Case Reports