Electrochemical hydrogenation of enones using a proton-exchange membrane reactor: selectivity and utility

Koichi Mitsudo; Haruka Inoue; Yuta Niki; Eisuke Sato; Seiji Suga

doi:10.3762/bjoc.18.107

Electrochemical hydrogenation of enones using a proton-exchange membrane reactor: selectivity and utility

Beilstein J Org Chem. 2022 Aug 19:18:1055-1061. doi: 10.3762/bjoc.18.107. eCollection 2022.

Authors

Koichi Mitsudo¹, Haruka Inoue¹, Yuta Niki¹, Eisuke Sato¹, Seiji Suga¹

Affiliation

¹ Division of Applied Chemistry, Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.

Abstract

Electrochemical hydrogenation of enones using a proton-exchange membrane reactor is described. The reduction of enones proceeded smoothly under mild conditions to afford ketones or alcohols. The reaction occurred chemoselectively with the use of different cathode catalysts (Pd/C or Ir/C).

Keywords: PEM reactor; enone; hydrogenation; iridium; palladium.

Grants and funding

This work was supported in part by JST CREST Grant No. JP65R1204400, Japan, JSPS KAKENHI Grant Number JP19K05477, JP19K05478, and JP22H02122.