On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects

Biomater Transl. 2022 Jun 28;3(2):142-151. doi: 10.12336/biomatertransl.2022.02.006. eCollection 2022.

Abstract

Polyether-ether-ketone (PEEK) is widely used in producing prosthesis and have gained great attention for repair of large bone defect in recent years with the development of additive manufacturing. This is due to its excellent biocompatibility, good heat and chemical stability and similar mechanical properties which mimics natural bone. In this study, three replicates of rectilinear scaffolds were designed for compression, tension, three-point bending and torsion test with unit cell size of 0.8 mm, a pore size of 0.4 mm, strut thickness of 0.4 mm and nominal porosity of 50%. Stress-strain graphs were developed from experimental and finite element analysis models. Experimental Young's modulus and yield strength of the scaffolds were measured from the slop of the stress-strain graph to be 395 and 19.50 MPa respectively for compression, 427 and 6.96 MPa respectively for tension, 257 and 25.30 MPa respectively for three-point bending and 231 and 12.83 MPa respectively for torsion test. The finite element model was found to be in good agreement with the experimental results. Ductile fracture of the struct subjected to tensile strain was the main failure mode of the PEEK scaffold, which stems from the low crystallinity of additive manufacturing PEEK. The mechanical properties of porous PEEK are close to those of cancellous bone and thus are expected to be used in additive manufacturing PEEK bone implants in the future, but the lower yield strength poses a design challenge.

Keywords: PEEK scaffold; additive manufacturing; bone scaffold; finite element analysis; lattice structure; mechanical behaviour.

Grants and funding

The study was financially supported by National Key R&D Program of China (No. 2018YFE0207900); Natural Science Basic Research Program of ShaanXi Province (No. 2022JQ-378); The EU via the H2020-MSCA-RISE-2016 Program (No. 734156); Engineering and Physical Sciences Research Council via DTP CASE Programme (No. EP/T517793/1); and Royal Society via an International Exchange Program (No. IEC\NSFC\191253).