Ultrasensitive tumour-agnostic non-invasive detection of colorectal cancer recurrence using ctDNA methylation

Clin Transl Med. 2022 Sep;12(9):e1015. doi: 10.1002/ctm2.1015.

Yu Xiao^{1

2}, Xiaodong Wang³, Hong Weng^{4

5}, Zhao Ding^{6

7}, Kaiyu Qian^{1

2}, Wan Jin⁸, Sen Lu⁹, Lingao Ju^{1

10}, Zhiwen He⁹, Gang Wang^{1

2}, Xiaoyu Xie^{6

7}, Dongmei Liu⁸, Zhou Fan⁶, Kai Wu⁸, Sheng Li^{1

2}, Huanhuan Guo⁸, Guofeng Qian¹¹, Wei Jiang^{1

10

12}, Yunji Leng⁸, Junpeng Zhao⁸, Xinyue Cao¹³, Minsheng Peng^{14

15}, Congqing Jiang^{6

7}, Li Li³, Yi Zhang⁸, Xinghuan Wang^{2

4

5

10

12}

¹ Department of Biological Repositories, Zhongnan Hospital of Wuhan University, Wuhan, China.
² Human Genetic Resource Preservation Center of Hubei Province, Wuhan, China.
³ Department of Gastroenterology Surgery, West China Hospital of Sichuan University, Chengdu, China.
⁴ Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
⁵ Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
⁶ Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.
⁷ Clinical Center of Intestinal and Colorectal Diseases of Hubei Province, Wuhan, China.
⁸ Euler Technology, ZGC Life Sciences Park, Beijing, China.
⁹ Department of Colorectal and Anal Surgery, The First Affiliated Hospital of Zhejiang University, Hangzhou, China.
¹⁰ Wuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan, China.
¹¹ Department of Endocrinology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China.
¹² Medical Research Institute, Wuhan University, Wuhan, China.
¹³ Clinical Trial Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
¹⁴ State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
¹⁵ University of Academy of Sciences, Kunming College of Life Science, Kunming, China.

No abstract available

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