Short-term Postoperative Outcomes of Colorectal Cancer Patients With Chronic Renal Failure on Dialysis

In Vivo. 2022 Sep-Oct;36(5):2461-2464. doi: 10.21873/invivo.12981.

Abstract

Background/aim: Surgery for dialysis patients requires special attention because of their physical characteristics. This study aimed to investigate the short-term postoperative outcomes of colorectal cancer patients with chronic renal failure (CRF) on dialysis and aimed to investigate safer treatment options for these patients.

Patients and methods: A total of 1,504 colorectal cancer patients who underwent primary resection between January 2008 and December 2018 were included. A retrospective analysis of clinical data, preoperative tumor markers (carcinoembryonic antigen and carbohydrate antigen 19-9), and the Clavien-Dindo (CD) classification was performed. Patients were stratified into Groups A and B based on their need for dialysis or not, respectively.

Results: There were 20 and 1,484 patients in Groups A and B, respectively. No differences were observed regarding age, body mass index, and preoperative tumor markers. The rate of laparoscopic surgery was significantly lower in Group A than in Group B. There was one mortality in Group A due to pulmonary disease. Group A had a significantly higher rate of complications.

Conclusion: CRF patients on dialysis who underwent colorectal cancer surgery tended to be ruled out of laparoscopic surgery, and their rates of postoperative complications were higher.

Keywords: Colorectal cancer; chronic renal failure; dialysis.

MeSH terms

  • Biomarkers, Tumor
  • Colorectal Neoplasms* / complications
  • Colorectal Neoplasms* / pathology
  • Colorectal Neoplasms* / surgery
  • Humans
  • Kidney Failure, Chronic* / complications
  • Kidney Failure, Chronic* / therapy
  • Renal Dialysis / adverse effects
  • Retrospective Studies

Substances

  • Biomarkers, Tumor