Oregano as a potential source of antidiabetic agents

J Food Biochem. 2022 Dec;46(12):e14388. doi: 10.1111/jfbc.14388. Epub 2022 Sep 13.

Abstract

Oregano is the name given to a great variety of herbs belonging mainly to the Lamiaceae and Verbenaceae botanical families. Oregano species are rich sources of phytochemicals such as phenolic compounds like rosmarinic acid, salvianolic acid, and luteolin, among others. A few articles have previously accessed some potential pharmacological bioactivities of oregano plants; however, none has focused on the antidiabetic studies. This review aims to summarize recent studies about the potential effect of phenolic compounds from oregano plant species. The reports were retrieved from electronic databases such as PubMed, Web of Science, National Center for Biotechnology Information (NCBI), and Scopus. In addition, articles related to the mentioned topics and published between 2004-2022 were selected. The results from this study show that the antidiabetic pharmacological reports of oregano phenolic compounds are mainly in vitro reports. Therefore, the diversity of oregano species yields a broad variety of phenolic constituents, where preclinical and clinical studies are strongly recommended.

Keywords: diabetes; flavonoids; oregano; phenolic acids; polyphenols.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Hypoglycemic Agents / pharmacology
  • Lamiaceae* / chemistry
  • Origanum* / chemistry
  • Phenols
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology

Substances

  • Plant Extracts
  • Hypoglycemic Agents
  • Phenols