Acetaminophen-induced Stevens-Johnson syndrome with lethal lung injury: A case report

Ryota Nakamura; Fumihiro Ochi; Toshiyuki Chisaka; Toshihiro Jogamoto; Mariko Eguchi

doi:10.1002/ccr3.6294

Acetaminophen-induced Stevens-Johnson syndrome with lethal lung injury: A case report

Clin Case Rep. 2022 Sep 5;10(9):e6294. doi: 10.1002/ccr3.6294. eCollection 2022 Sep.

Authors

Ryota Nakamura¹, Fumihiro Ochi^{1

2}, Toshiyuki Chisaka¹, Toshihiro Jogamoto¹, Mariko Eguchi¹

Affiliations

¹ Department of Pediatrics Ehime University Graduate School of Medicine Toon Ehime Japan.
² Department of Pediatrics Ehime Prefectural Niihama Hospital Niihama Ehime Japan.

Abstract

Stevens-Johnson syndrome (SJS) with respiratory distress can lead to fatal outcomes. However, there are a few reports of drug-induced lung injury with diffuse alveolar damage caused by acetaminophen, the most severe type. Here, we describe a fatal case of acetaminophen-induced SJS in a child with irreversible lung lesions.

Keywords: Stevens–Johnson syndrome; acetaminophen; acute respiratory distress syndrome; drug lymphocyte stimulation test.

Publication types

Case Reports