Influence of Temporal Interference Stimulation Parameters on Point Neuron Excitability

Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul:2022:2365-2368. doi: 10.1109/EMBC48229.2022.9871641.

Abstract

Temporal interference (TI) stimulation is a technique in which two high frequency sinusoidal electric fields, oscillating at a slightly different frequency are sent into the brain. The goal is to achieve stimulation at the place where both fields interfere. This study uses a simplified version of the Hodgkin - Huxley model to analyse the different parameters of the TI-waveform and how the neuron reacts to this waveform. In this manner, the underlying mechanism of the reaction of the neuron to a TI -signal is investigated. Clinical relevance- This study shows the importance of the parameter choice of the temporal interference waveform and provides insights into the underlying mechanism of the neuronal response to a beating sine for the application of temporal interference stimulation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain*
  • Neurons* / physiology