Information needs of patients considering oral immunotherapy for food allergy

Clin Exp Allergy. 2022 Dec;52(12):1391-1402. doi: 10.1111/cea.14225. Epub 2022 Sep 21.

Abstract

While the historic management of food allergy includes avoidance strategies and allergic reaction treatment, oral immunotherapy (OIT) approaches have become more commonly integrated into therapeutic approaches. International guidelines, phase 3 trials and real-world experience have supported the implementation of this procedure. However, OIT is an elective, rarely curative procedure with inherent risks that necessitates an increased degree of health literacy for the patients and families. Families assume the responsibility of amateur healthcare providers to ensure the daily safe administration of the allergenic food. As such, it is incumbent upon physicians to ensure that families are prepared for this role. A thorough educational and shared decision-making approach is necessary during the counselling and consent process to adequately inform the families. Educated discussion about the efficacy and patient-centred effectiveness, therapeutic alternatives and family goals is required to align physician and patient expectations. A frank discussion about the struggles, practical challenges, risks and contraindications can help to develop an understanding of the risk mitigation strategies employed to maintain safety. Physicians should develop a proactive approach to educate families about this, at times, burdensome procedure. This educational approach should encourage ongoing support starting prior to consent through the maintenance visits. By preparing families for their unique management role, physicians can help ensure the safe and successful integration of OIT into the therapeutic offering for the management of food allergies.

Keywords: Shared decision-making; anaphylaxis; education; food allergy; immunotherapy andtolerance induction; quality-of-life.

Publication types

  • Review

MeSH terms

  • Administration, Oral
  • Allergens
  • Desensitization, Immunologic* / adverse effects
  • Desensitization, Immunologic* / methods
  • Food Hypersensitivity*
  • Humans
  • Immunotherapy

Substances

  • Allergens