Fluctuating Hyperthyroidism and Hypothyroidism in Graves' Disease: The Swinging Between Two Clinical Entities

Cureus. 2022 Aug 5;14(8):e27715. doi: 10.7759/cureus.27715. eCollection 2022 Aug.

Abstract

Autoimmune thyroid disorders are frequently encountered in clinical practice and consist of a spectrum ranging from Graves' hyperthyroidism to Hashimoto's hypothyroidism. Generally, patients with autoimmune thyroid disorders will lean towards one end of the spectrum or the other, with fluctuations between hyper- and hypothyroidism rarely seen. This is especially the case when persistent hyperthyroidism occurs after a prolonged period of hypothyroidism. Here, we present a case of a young female patient initially presenting with Graves' disease with a previous history of hypothyroidism.

Keywords: graves's disease; hashimoto's hypothyroidism; hyperthyroid; hypothyroid; thyroid peroxidase antibodies.

Publication types

  • Case Reports