The Identification and Clinical Applications of Mutated Antigens in the Era of Immunotherapy

Cancers (Basel). 2022 Aug 31;14(17):4255. doi: 10.3390/cancers14174255.

Abstract

The era of personalized cancer therapy is here. Advances in the field of immunotherapy have paved the way for the development of individualized neoantigen-based therapies that can translate into favorable treatment outcomes and fewer side effects for patients. Addressing challenges related to the identification, access, and clinical application of neoantigens is critical to accelerating the development of individualized immunotherapy for cancer patients.

Keywords: immunotherapy; mutated antigen; neoantigen; tumor-associated antigens.

Publication types

  • Review

Grants and funding

No funding was received for this review article.