Gastroduodenal neuroendocrine neoplasms including gastrinoma - update of the diagnostic and therapeutic guidelines (recommended by the Polish Network of Neuroendocrine Tumours) [Nowotwory neuroendokrynne żołądka i dwunastnicy z uwzględnieniem gastrinoma - uaktualnione zasady postępowania (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)]

Endokrynol Pol. 2022;73(3):455-490. doi: 10.5603/EP.a2022.0051.

Abstract

After another meeting of experts of the Polish Network of Neuroendocrine Tumours, updated recommendations for the management of patients with gastric and duodenal neuroendocrine neoplasms, including gastrinoma, have been issued. As before, the epidemiology, pathogenesis and clinical symptoms of these neoplasms have been discussed, as well as the principles of diagnostic procedures, including biochemical and histopathological diagnostics and tumour localisation, highlighting the changes introduced in the recommendations. Updated principles of therapeutic management have also been presented, including endoscopic and surgical treatment, and the options of pharmacological and radioisotope treatment. The importance of monitoring patients with gastric and duodenal NENs, including gastrinoma, has also been emphasised.

Keywords: diagnostics; duodenum; gastrinoma; neuroendocrine neoplasms; recommendations; stomach; therapy.

MeSH terms

  • Duodenal Neoplasms* / diagnosis
  • Duodenal Neoplasms* / therapy
  • Endocrinology*
  • Gastrinoma* / diagnosis
  • Gastrinoma* / therapy
  • Humans
  • Medical Oncology
  • Neuroendocrine Tumors* / diagnosis
  • Neuroendocrine Tumors* / therapy
  • Pancreatic Neoplasms* / diagnosis
  • Pancreatic Neoplasms* / therapy
  • Poland