BACKGROUND Breast cancer is the most common cancer in women and the most common cause of spinal metastasis, and it may recur months to years after treatment. CASE REPORT A 41-year-old woman, recovered from breast cancer, presented to a chiropractor with acute-on-chronic 3-week history of low back pain radiating to the right leg. She had seen 2 providers previously; lumbar spondylosis had been diagnosed via radiography. Given her recent symptom progression and cancer history, the chiropractor ordered lumbar magnetic resonance imaging, revealing L5 vertebral marrow replacement, suggestive of metastasis. The chiropractor referred her to an oncologist. While awaiting biopsy and oncologic treatments, the oncologist cleared the patient to receive gentle spinal traction and soft tissue manipulation, which alleviated her back pain. The patient continued radiation and chemotherapy, with low back pain remaining improved over 18 months. A literature review identified 7 previous cases of women presenting to a chiropractor with breast cancer metastasis. Including the current case, most had spinal pain and vertebral metastasis (75%) and history of breast cancer (88%) diagnosed a mean 5±3 years prior. CONCLUSIONS This case illustrates a woman with low back pain due to recurrent metastatic breast cancer, identified by a chiropractor, and the utility of a multidisciplinary approach to pain relief during oncologic care. Our literature review suggests that although uncommon, such patients can present to chiropractors with spinal pain from vertebral metastasis and have a known history of breast cancer. Conservative therapies should be used cautiously and under oncologic supervision in such cases.