Effect of Intracapsular Pressure on Decompression Effectiveness

Xianbin Xiong; Changshun Li; Li Guo; Yuanyuan Wu; Yi Wang; Xiaomeng Song

doi:10.1016/j.identj.2022.06.023

Effect of Intracapsular Pressure on Decompression Effectiveness

Int Dent J. 2022 Dec;72(6):839-846. doi: 10.1016/j.identj.2022.06.023. Epub 2022 Aug 30.

Authors

Xianbin Xiong¹, Changshun Li², Li Guo¹, Yuanyuan Wu¹, Yi Wang¹, Xiaomeng Song³

Affiliations

¹ Key Laboratory of Oral Diseases of Jiangsu Province and Stomatological Institute of Nanjing Medical University, Nanjing Medical University, Nanjing, China; Department of Oral and Maxillofacial Surgery, Affiliated Stomatological Hospital, Nanjing Medical University, Nanjing, China.
² Key Laboratory of Oral Diseases of Jiangsu Province and Stomatological Institute of Nanjing Medical University, Nanjing Medical University, Nanjing, China; Department of Affiliated Stomatological Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
³ Key Laboratory of Oral Diseases of Jiangsu Province and Stomatological Institute of Nanjing Medical University, Nanjing Medical University, Nanjing, China; Department of Oral and Maxillofacial Surgery, Affiliated Stomatological Hospital, Nanjing Medical University, Nanjing, China. Electronic address: xiaomengsong@njmu.edu.cn.

Abstract

Aim: The objective of this research was to analyse the correlation between intracapsular pressure and shrinkage rate of cystic lesion volume at different time points after decompression and to evaluate the relationship between the concentration of interleukin-1α (IL-1α) in cystic fluid and intracapsular pressure.

Methods: Fifty patients with jaw cystic lesions who underwent decompression were included. We measured the intracapsular pressure and IL-1α concentration in the cyst fluid. Moreover, we calculated the rate of shrinkage (RS) of cystic cavity volume at different time points. In addition, data on age, sex, preoperative cystic cavity volume, and lesion location were collected. Linear correlation analysis and variance analysis were used for statistical analysis.

Results: Fastest volume decline was observed between 0 and 3 months after surgery; the average RS_0-3 was 45.71%. RS_3-6 presented the second-fastest volume decline, with an average of 17.46%, and RS_6-12 presented the slowest volume decline, with an average of 3.933%. A statistically significant difference in RS was observed amongst the 3 time points (P < .0001). RS_0-3 was negatively correlated with intracapsular pressure (r = -0.6326, n = 50, P < .0001). A negative correlation between the preoperative cystic cavity volume and intracapsular pressure (r = -0.6384, n = 50, P < .001) was also observed. A significant positive correlation was observed between preoperative cystic cavity volume and RS_0-3 (r = 0.611, n = 50, P < .0001). Moreover, a significant positive correlation was observed between the intracapsular pressure and IL-1α concentration in the cystic fluid (r = 0.03477, n = 50, P < .0001).

Conclusions: Intracapsular pressure and the preoperative volume were the factors that affected the RS during the first 3 months after surgery. Therefore, the effectiveness of decompression can be evaluated by the intracapsular pressure and preoperative volume.

Keywords: Decompression; IL-1α; Intracapsular pressure; Jaw cystic lesions.

MeSH terms

Decompression, Surgical*
Humans
Jaw Cysts* / surgery
Treatment Outcome