Analysis of severity in ischemic stroke patients with coronary artery disease in the telestroke network

Future Cardiol. 2022 Sep;18(10):797-807. doi: 10.2217/fca-2022-0059. Epub 2022 Sep 2.

Abstract

Aim: This study investigated demographic and clinical risk factors associated with severity in acute ischemic stroke (AIS) patients with a history of coronary artery disease (CAD). Materials & methods: Multivariate logistic regression models were used to determine specific factors associated with worsening or improving neurologic functions among AIS patients with CAD treated in the telestroke. Results: AIS patients with CAD, peripheral vascular disease (OR: 3.995; 95% CI: 1.035-15.413; p = 0.044) and hypertension (OR: 6.056; 95% CI: 1.207-30.374; p = 0.029) were associated with worsening neurologic functions. Conclusion: Our findings suggest the need to develop strategic management to improve the care of AIS patients with a history of CAD that present with hypertension and peripheral vascular disease in the telestroke network.

Keywords: NIHSS score; coronary artery disease; ischemic stroke; telestroke network.

Plain language summary

This study investigated risk factors that contribute to poor outcomes in stroke patients with a history of coronary artery disease. We used advanced statistical approach to identify risk that contribute to poor neurologic functions. We observed that peripheral vascular disease and hypertension were associated with worsening neurologic functions. Our findings suggest the need to develop management plans to improve the care of acute ischemic stroke patients with a history of coronary artery disease that present with hypertension and peripheral vascular disease in the telestroke network.

MeSH terms

  • Coronary Artery Disease* / complications
  • Coronary Artery Disease* / diagnosis
  • Humans
  • Hypertension* / complications
  • Ischemic Stroke*
  • Peripheral Vascular Diseases* / complications
  • Risk Factors
  • Stroke* / complications
  • Stroke* / etiology