Intestinal virome: An important research direction for alcoholic and nonalcoholic liver diseases

World J Gastroenterol. 2022 Jul 14;28(26):3279-3281. doi: 10.3748/wjg.v28.i26.3279.

Abstract

In recent years, the interaction between the gut microflora and liver diseases has attracted much attention. The intestinal microflora is composed of bacteria, archaea, fungi and viruses. There are few studies on the intestinal virome, and whether it has a causal relationship with bacterial changes in the gut is still unclear. However, it is undeniable that the intestinal virome is also a very important portion of the blueprint for the development of liver diseases and the diagnosis and therapeutic modalities in the future.

Keywords: Alcoholic fatty liver disease; Fatty liver disease; Gut microbiome; Intestinal virome; Nonalcoholic fatty liver disease.

MeSH terms

  • Bacteria
  • Gastrointestinal Microbiome*
  • Humans
  • Non-alcoholic Fatty Liver Disease* / etiology
  • Virome
  • Viruses*