The emerging role of skeletal muscle as a modulator of lipid profile the role of exercise and nutrition

Lipids Health Dis. 2022 Aug 30;21(1):81. doi: 10.1186/s12944-022-01692-0.

Abstract

The present article aims to discuss the hypothesis that skeletal muscle per se but mostly its muscle fiber composition could be significant determinants of lipid metabolism and that certain exercise modalities may improve metabolic dyslipidemia by favorably affecting skeletal muscle mass, fiber composition and functionality. It discusses the mediating role of nutrition, highlights the lack of knowledge on mechanistic aspects of this relationship and proposes possible experimental directions in this field.

Keywords: Dyslipidemia; Exercise protocols; Intramuscular triglycerides; Lipid profile; Muscle fibers; Skeletal muscle.

MeSH terms

  • Exercise* / physiology
  • Lipid Metabolism
  • Lipids
  • Muscle Fibers, Skeletal / metabolism
  • Muscle, Skeletal* / metabolism

Substances

  • Lipids