Research articles on the mechanisms of acupuncture in the treatment of dysmenorrhea model in rats were retrieved from PubMed and China National Knowledge Infrastructure (CNKI). As revealed by the analysis, the underlying mechanisms were mainly related to the regulation of endocrine system and neurotransmitters, the modulation of immunoinflammatory responses, the improvement of uterine microcirculation, and reduction of oxidative stress. In the future, research should be carried out to explore the mechanism of acupuncture in relieving dysmenorrhea via acupoints and the specific mechanism of classical acupoints, so as to enrich the multi-pathway mechanisms of acupuncture in treating dysmenorrhea and provide more scientific basis for optimizing clinical modalities for primary dysmenorrhea treatment by acupuncture.
通过检索中国期刊全文数据库及PubMed数据库, 对筛选出的针刺治疗模拟原发性痛经(PD)大鼠机制研究文献进行分析, 发现针刺治疗PD的机制包括调控内分泌与镇痛物质、调节免疫炎性反应、改善子宫血流、减轻氧化应激等方面。不同针刺干预方式对经穴缓解PD的效应差异机制、经典效穴的特异性机制值得进一步研究, 以完善针刺治疗PD的多途径机制研究, 为临床优化针刺治疗PD方案提供科学依据。.
Keywords: Acupuncture; Mechanism; Rats model of dysmenorrheain.