Polysaccharides from Rhizoma Atractylodis Macrocephalae: A Review on Their Extraction, Purification, Structure, and Bioactivities

Lei Luo; Jin Cai; Zhang Zhou; Wenqian Tang; Juan Xue; Jinxin Liu; Hongfei Hu; Fan Yang

doi:10.1155/2022/2338533

Polysaccharides from Rhizoma Atractylodis Macrocephalae: A Review on Their Extraction, Purification, Structure, and Bioactivities

Evid Based Complement Alternat Med. 2022 Aug 17:2022:2338533. doi: 10.1155/2022/2338533. eCollection 2022.

Authors

Lei Luo¹, Jin Cai², Zhang Zhou³, Wenqian Tang¹, Juan Xue⁴, Jinxin Liu⁵, Hongfei Hu⁵, Fan Yang¹

Affiliations

¹ Department of Health Management Center, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan 430070, China.
² Department of Hepatobiliary Surgery, The Second People's Hospital of China Three Gorges University, Yichang 443000, China.
³ Department of Anesthesiology, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430035, China.
⁴ Department of Gastroenterology, Hubei Provincial Hospital of Traditional Chinese and Western Medicine, Wuhan 430015, China.
⁵ School of Clinical Medical, Hubei University of Chinese Medicine, Wuhan 443000, China.

Abstract

Rhizoma Atractylodes macrocephala polysaccharide (RAMP), the main bioactive compound extracted from Rhizoma Atractylodes macrocephala (RAM), exhibits various biological activities in in vivo and in vitro methods, such as anti-inflammatory, antioxidant, antitumor, immunomodulatory, hepatoprotective effects, and other functions. This review systematically summarizes the recent research progress on the extraction, purification, structural characteristics, and biological activities of RAMP. We hope to provide a theoretical basis for further research on the application of RAMP in the fields of biomedicine and food.

Publication types

Review