Neurotrophic factors in the porcine ovary: Their effects on follicular growth, oocyte maturation, and developmental competence

Mirae Kim; Sang-Hwan Hyun

doi:10.3389/fvets.2022.931402

Neurotrophic factors in the porcine ovary: Their effects on follicular growth, oocyte maturation, and developmental competence

Front Vet Sci. 2022 Aug 10:9:931402. doi: 10.3389/fvets.2022.931402. eCollection 2022.

Authors

Mirae Kim^{1

2}, Sang-Hwan Hyun^{1

2

3}

Affiliations

¹ Laboratory of Veterinary Embryology and Biotechnology, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, South Korea.
² Institute of Stem Cell and Regenerative Medicine, Chungbuk National University, Cheongju, South Korea.
³ Graduate School of Veterinary Biosecurity and Protection, Chungbuk National University, Cheongju, South Korea.

Abstract

Pigs are cost-effective industrial animals because they produce a large number of offspring and have shorter rebreeding intervals compared with other animals, such as non-human primates. The reproductive physiology of pigs has been studied over the past several decades. However, there is not enough research on the effects of the neurotrophic factors on the ovarian physiology and development in pigs. As the ovary is a highly innervated organ, various neurotrophic factors during ovarian development can promote the growth of nerve fibers and improve the development of ovarian cells. Thus, investigating the role of neurotrophic factors on ovarian development, and the relationship between neurotrophic factors and porcine female reproduction is worth studying. In this review, we focused on the physiological roles of various neurotrophic factors in porcine ovaries and summarized the current status of the studies related to the relationship between neurotrophic factors and porcine ovarian development.

Keywords: female reproduction; folliculogenesis; neurotrophic factors; ovarian development; pig.

Publication types

Review