What Are the Biomechanical Properties of an Aortic Aneurysm Associated with Quadricuspid Aortic Valve?

J Clin Med. 2022 Aug 20;11(16):4897. doi: 10.3390/jcm11164897.

Abstract

Association of quadricuspid aortic valve (QAV) with ascending aortic aneurysms (AsAA) is rare. A 63-year-old female with hypertension was found (on MRI) to have an ascending aortic aneurysm (52 mm in maximum diameter) and dilatation at the level of the sinotubular junction (38 mm in diameter) associated with quadricuspid aortic valve. An ascending aortic wall replacement surgery was performed. In this study, we focus on the behavior of the aorta associated with QAV considering the in vitro biomechanical characteristics and histology. The properties of QAV are closer to bicuspid aortic valve than tricuspid aortic valve, but with higher wall thickness.

Keywords: ascending aortic aneurysms; biomechanical properties; histology; quadricuspid aortic valve.