Atorvastatin reduces zoledronic acid-induced osteonecrosis of the jaws of rats

Bone. 2022 Nov:164:116523. doi: 10.1016/j.bone.2022.116523. Epub 2022 Aug 17.
No abstract available

Keywords: Atorvastatin; Bisphosphonates; Osteonecrosis; Wnt signaling; Zoledronic acid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Atorvastatin / adverse effects
  • Bisphosphonate-Associated Osteonecrosis of the Jaw* / drug therapy
  • Bone Density Conservation Agents* / adverse effects
  • Diphosphonates / pharmacology
  • Jaw
  • Osteonecrosis* / chemically induced
  • Osteonecrosis* / drug therapy
  • Rats
  • Zoledronic Acid / adverse effects

Substances

  • Bone Density Conservation Agents
  • Diphosphonates
  • Zoledronic Acid
  • Atorvastatin