Ring-opening of non-activated aziridines with [11C]CO2 via novel ionic liquids

RSC Adv. 2022 Aug 2;12(33):21417-21421. doi: 10.1039/d2ra03966d. eCollection 2022 Jul 21.

Abstract

Novel ionic liquids based on DBU and DBN halide salts were developed as a catalytic system for ring-opening of non-activated aziridines with [11C]CO2. The ability of ionic liquids to activate aziridines represents a simple methodology for the synthesis of 11C-carbamates and can be extended for CO2-fixation in organic and radiochemistry.