Venous-arterial extracorporeal membrane oxygenation support for patients poisoned by Macleaya cordata

Perfusion. 2023 Nov;38(8):1751-1753. doi: 10.1177/02676591221122355. Epub 2022 Aug 16.

Abstract

Macleaya cordata is a Chinese herbal medicine containing a variety of highly cardiotoxic alkaloids, and might result in cardiac failure. Venous-arterial Extracorporeal membrane oxygenation (VA-ECMO) could be used as a therapeutic option in patients poisoned by Macleaya cordata complicating refractory cardiogenic shock or cardiac arrest. A 60-year-old man suffered from severe arrhythmia, cardiogenic shock and cardiac arrest after consuming Macleaya cordata. The patient received VA-ECMO support in the emergency department at 5 hours after hospitalization, and was weaned from VA-ECMO on day 4, and was discharged with complete clinical improvement on Day 12. VA-ECMO is an effective method in treating cardiogenic shock or cardiac arrest induced by severe poisoning from Chinese herbal medicine. Timely and appropriate interventions with venoarterial extracorporeal membrane oxygenation devices could improve clinical outcomes in these patients.

Keywords: Macleaya cordata; cardiac arrest; poisoning; venoarterial extracorporeal membrane oxygenation.

Publication types

  • Case Reports

MeSH terms

  • Drugs, Chinese Herbal* / poisoning
  • Extracorporeal Membrane Oxygenation*
  • Heart Arrest* / etiology
  • Humans
  • Male
  • Middle Aged
  • Poisons*
  • Retrospective Studies
  • Shock, Cardiogenic / etiology
  • Shock, Cardiogenic / therapy

Substances

  • Drugs, Chinese Herbal
  • Poisons