Editorial: Metabolism of anti-cancer drugs: Interplay involving pharmacology and pharmacokinetics

Front Oncol. 2022 Jul 29:12:972718. doi: 10.3389/fonc.2022.972718. eCollection 2022.

Tashinga E Bapiro¹, Rose Hayeshi², Collet Dandara^{3

4}

¹ Drug Metabolism & Pharmacokinetics (DMPK), Oncology R&D, AstraZeneca, Cambridge, United Kingdom.
² Department of Science and Innovation/North-West University (DSI/NWU) Preclinical Drug Development Platform, Faculty of Health Sciences, North-West University, Potchefstroom, South Africa.
³ Division of Human Genetics, Department of Pathology & Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
⁴ Platform for Pharmacogenomics Research and Translation Extramural Unit, South African Medical Research Council, Cape Town, South Africa.

No abstract available

Keywords: anticancer drugs; cytochrome P450; drug metabolism; drug-drug interactions; pharmacodynamics; pharmacokinetics.

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