Urinary tract infection is a colonisation of the urinary tract with uropathogenic bacteria, leading to an inflammatory response. The increasing antimicrobial resistance presents major challenges for both the individual and our society. The goal is to reduce antimicrobial resistance and pave the way for a new era in the management of recurrent urinary tract infections. This review describes the definitions of urinary tract infection (simple, recurrent, and complicated) as well as examination and treatment recommendations. The future and most common non-antibiotic alternatives are discussed.