Objective:To investigate the clinical and pathological features, treatment, prognostic and its influence factors of granulosa cell tumor of head and neck. Methods:The clinical medical records of 12 patients with head and neck granulosa cell tumor confirmed by pathology for diagnosis and treatment in Beijing Tongren Hospital affiliated to Capital Medical University were reviewed and collected. Results:The follow-up durations were 4-57 months, with a median of 23 months. The origination of twelve cases were reviewed: 3 cases of the vocal cords, 2 cases of the retroannular region, 1 cases of the ventricular bands, 1 cases of the interarytenoid region, 1 cases of the paraglottic space, 1 cases of the epiglottis, 1 cases of the soft palate, 1 cases of the ventricle of larynx, 1 cases of the trapezius muscle. All 12 patients were undergoing surgical treatment in our hospital, including one who had postoperative adjuvant radiotherapy after second operation. Conclusion:Granulosa cell tumor occurs in the head and neck, usually a benign tumor with diverse morphology, and its diagnosis is mainly based on tumor histopathological examination. Surgical local excision is used in most cases, especially minimally invasive surgery is recommended, with lower postoperative recurrence rate and better prognosis.
目的：探讨头颈部颗粒细胞瘤（GCT）的临床特征、病理表现、治疗手段、预后及其影响因素。 方法：回顾并收集在首都医科大学附属北京同仁医院诊治，经病理证实的12例头颈部GCT患者的临床病历资料。 结果：随访4～57个月，中位随访23个月。12例患者中，肿瘤原发于声带3例、环后区2例、室带1例、杓间区1例、声门旁间隙1例、会厌1例、软腭1例、喉室1例、斜方肌内1例。12例患者均接受手术治疗，其中1例二次手术并在术后辅助放射治疗。 结论：GCT好发于头颈部，通常为良性肿瘤，形态多样，其确诊主要依据肿瘤组织病理学检查。大多采用手术局部切除，尤其推荐微创手术，术后复发率较低，预后较好。.
Keywords: clinicopathological features; granulosa cell tumor; tumors of head and neck.
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