Decrease in CD8+CD45+CCR7+CD62L+ T cells in individuals vaccinated with Sinovac-CoronaVac following COVID-19 infection

Clin Immunol. 2022 Sep:242:109092. doi: 10.1016/j.clim.2022.109092. Epub 2022 Aug 6.

Abstract

Vaccines induce antibodies, but T cell responses are also important for protection against Coronavirus disease 2019. Here, we analyzed the frequency of memory T cells in infected and/or vaccinated individuals and observed a decrease in central memory T cells in individuals who were vaccinated following COVID-19 infection.

Keywords: COVID-19; Immune memory; T cells; Vaccination.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Viral
  • CD8-Positive T-Lymphocytes* / cytology
  • COVID-19 Vaccines* / immunology
  • COVID-19* / prevention & control
  • Humans
  • Memory T Cells / cytology
  • Vaccination

Substances

  • Antibodies, Viral
  • COVID-19 Vaccines