Excision of Postchemotherapy Residual Retroperitoneal Mass in Testicular Cancer

J Coll Physicians Surg Pak. 2022 Aug;32(8):1089-1091. doi: 10.29271/jcpsp.2022.08.1089.

Abstract

In this study, patients, who underwent excision of retroperitoneal mass following chemotherapy for testicular cancers from 2006 to 2016, were studied and followed till 2021. The clinical and oncological outcomes were measured. Among 338 patients, who were treated for TC during the entire study period, 38 (11.2%) underwent excision of the residual retroperitoneal mass. The mean age of these patients was 26.9±6.3 years. The majority were stage 3 testicular cancer. Complete resection with negative microscopic margins was achieved in the majority of cases i.e. 31 (81.6%). Damage to the collateral structures was seen in 12 (31.6%) cases. On histopathological examination, teratoma was seen in 18 (47.4%) of the cases followed by necrosis in 10 (26.3%). Complications were recorded in 12 (31.5%) cases, most were low grades. At five years of follow-up, 19 (50%) were disease-free, 25 (65.8%) were alive, and 9 (23.6%) were lost to follow-up. Five-year survival rates are lower than standard template-based retroperitoneal dissection, however, complications rates are comparable. Such complex surgeries should only be performed in high-volume centres. Key Words: Testicular neoplasms, Lymph node excision, Seminoma, Germ cell and embryonal.

MeSH terms

  • Adult
  • Humans
  • Lymph Node Excision
  • Male
  • Neoplasms, Germ Cell and Embryonal* / drug therapy
  • Neoplasms, Germ Cell and Embryonal* / surgery
  • Retroperitoneal Neoplasms* / drug therapy
  • Retroperitoneal Neoplasms* / pathology
  • Retroperitoneal Neoplasms* / surgery
  • Retroperitoneal Space / pathology
  • Retrospective Studies
  • Testicular Neoplasms* / drug therapy
  • Testicular Neoplasms* / pathology
  • Testicular Neoplasms* / surgery
  • Young Adult

Supplementary concepts

  • Testicular Germ Cell Tumor