Structural insights into Cas9 mismatch: promising for development of high-fidelity Cas9 variants

Signal Transduct Target Ther. 2022 Aug 4;7(1):271. doi: 10.1038/s41392-022-01139-z.

Honghai Tang^{1

2

3}, Daqi Wang^{1

2

3}, Yilai Shu^{4

5

6}

¹ ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China.
² Institute of Biomedical Science, Fudan University, Shanghai, China.
³ NHC Key Laboratory of Hearing Medicine (Fudan University), Shanghai, China.
⁴ ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China. yilai_shu@fudan.edu.cn.
⁵ Institute of Biomedical Science, Fudan University, Shanghai, China. yilai_shu@fudan.edu.cn.
⁶ NHC Key Laboratory of Hearing Medicine (Fudan University), Shanghai, China. yilai_shu@fudan.edu.cn.

No abstract available

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