[Clinicopathological features of SMARCA4-deficient tumors]

Zhonghua Bing Li Xue Za Zhi. 2022 Aug 8;51(8):792-798. doi: 10.3760/cma.j.cn112151-20220226-00131.

[Article in Chinese]

¹ Department of Pathology, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, China.
² Department of General Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, China.
³ Department of Pathology, Fudan University, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Shanghai 200032, China.
⁴ Department of Pathology, the Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University, Suzhou 215153, China.
⁵ Department of Pathology, Zhangzhou Municipal Hospital of Fujian Medical University, Zhangzhou 363000, China.

Abstract

SMARCA4缺失性肿瘤是一组少见的高侵袭性肿瘤，因缺乏特异性分化易被误诊。提高对这一组新病种的认识不仅有助于诊断和鉴别诊断，也可为临床治疗和预后判断提供重要信息。本文对各系统SMARCA4缺失性肿瘤加以总结，介绍其临床病理学特征、免疫表型及鉴别诊断。.