Ten-Year Trends of Hepatitis A Seroprevalence in People Living with HIV in Korea

Shinwon Lee; Jeong Eun Lee; Soon Ok Lee; Yong Ki Sim; Sun Hee Lee

doi:10.3947/ic.2022.0062

Ten-Year Trends of Hepatitis A Seroprevalence in People Living with HIV in Korea

Infect Chemother. 2022 Sep;54(3):529-533. doi: 10.3947/ic.2022.0062. Epub 2022 Jul 22.

Authors

Shinwon Lee¹, Jeong Eun Lee¹, Soon Ok Lee¹, Yong Ki Sim¹, Sun Hee Lee²

Affiliations

¹ Department of Internal Medicine, Pusan National University School of Medicine and Medical Research Institute, Pusan National University Hospital, Busan, Korea.
² Department of Internal Medicine, Pusan National University School of Medicine and Medical Research Institute, Pusan National University Hospital, Busan, Korea. zzanmery@gmail.com.

Abstract

Epidemiological information on hepatitis A among people living with HIV (PLHIV) in Korea is scarce. This retrospective study was performed at a tertiary care hospital and included 756 PLHIV with anti- hepatitis A virus (HAV) IgG tests. Between 2012 and 2021, the age at anti-HAV IgG seroconversion is gradually delayed, and the proportion of individuals susceptible to HAV infection increased among adult PLHIV in Korea. The independent risk factors for HAV seropositivity were female sex and HBs antigen (Ag) positivity. Therefore, HAV vaccination is highly recommended for young PLHIV, especially for women or HBsAg-positive individuals.

Keywords: AIDS; HAV; HIV; Hepatitis A; Seroprevalence.

Grants and funding

Pusan National University/Korea