Feeding and lipophagy: it takes guts to deliver

EMBO J. 2022 Sep 1;41(17):e112180. doi: 10.15252/embj.2022112180. Epub 2022 Aug 3.

Abstract

Refeeding after a period of starvation is known to suppress autophagy in the liver. Surprising new work by Seok et al (2022) shows that refeeding activates lipophagy in the intestine, which may help fats in our diet to be efficiently processed after a meal.

MeSH terms

  • Autophagy / physiology
  • Humans
  • Lipid Metabolism*
  • Liver / metabolism
  • Starvation* / metabolism