Study on the Relationship between AAD and Clinical Features in Emergency Ward Patients and the Application Effect of Probiotics

Contrast Media Mol Imaging. 2022 Jul 11:2022:6164843. doi: 10.1155/2022/6164843. eCollection 2022.

Abstract

In order to investigate the influencing factors of AAD in the emergency ward and the clinical effect of probiotics, 100 AAD patients admitted to the emergency ward of our hospital from January 2021 to January 2022 and 100 healthy physical examination subjects are selected for conducting clinical trials. The subjects are, respectively, included in the AAD group and the healthy group. By using the random number table method, 100 patients in the AAD group are randomly divided into the probiotic group and traditional group, with 50 patients in each group. The traditional group receives conventional treatment, and the probiotic group is treated with Clostridium caseinate bifidobacterial probiotics additionally. Multivariate logistic analysis is performed on the risk factors for AAD, and the comparison of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and the intestinal microflora of the different groups before and after treatment is conducted. The experimental result reveals that probiotics treatment for AAD patients can reduce inflammatory response and promote intestinal colonization of beneficial bacteria such as bifidobacteria.

Publication types

  • Randomized Controlled Trial
  • Retracted Publication

MeSH terms

  • Anti-Bacterial Agents / adverse effects
  • Diarrhea* / chemically induced
  • Diarrhea* / microbiology
  • Emergency Service, Hospital
  • Humans
  • Multivariate Analysis
  • Probiotics* / therapeutic use

Substances

  • Anti-Bacterial Agents