Spontaneous Coronary Artery Dissection Following SARS-CoV-2-Associated Multisystem Inflammatory Syndrome

Anthony M Pettinato; Feria A Ladha; Jan Zeman; Joseph J Ingrassia

doi:10.7759/cureus.26479

Spontaneous Coronary Artery Dissection Following SARS-CoV-2-Associated Multisystem Inflammatory Syndrome

Cureus. 2022 Jul 1;14(7):e26479. doi: 10.7759/cureus.26479. eCollection 2022 Jul.

Authors

Anthony M Pettinato¹, Feria A Ladha¹, Jan Zeman², Joseph J Ingrassia³

Affiliations

¹ Medicine, University of Connecticut School of Medicine, Farmington, USA.
² Department of Internal Medicine, University of Connecticut School of Medicine, Farmington, USA.
³ Interventional Cardiology, Hartford Hospital, Hartford, USA.

Abstract

Spontaneous coronary artery dissection (SCAD) is an underdiagnosed cause of acute coronary syndrome, myocardial infarction, and sudden cardiac death. During the coronavirus disease 2019 (COVID-19) pandemic, a multisystem inflammatory syndrome (MIS) emerged that is incompletely understood. While the involvement of numerous organ systems has been described, the potential cardiovascular manifestations, such as myocarditis, arterial thrombosis, or SCAD, are particularly worrisome. Here, we present a case of MIS that was preceded by an unremarkable case of COVID-19 and followed by the development of SCAD. This case highlights the importance of furthering our understanding of the potential sequelae of COVID-19 and of the potential relationship between SCAD and MIS.

Keywords: covid-19; mis-a; multisystem inflammatory syndrome; myocardial infarction; spontaneous coronary artery dissection.

Publication types

Case Reports