Lipid profile, apolipoproteins A-1 and B in owl monkeys (Aotus infulatus) in captivity

J Med Primatol. 2022 Dec;51(6):367-373. doi: 10.1111/jmp.12607. Epub 2022 Aug 2.

Abstract

Background: Owl monkeys (Aotus infulatus) are frequently affected by heart diseases and, as in humans, dyslipidemia is one of the predisposing factors for adverse cardiovascular events. In view of this, the study of the lipid profile and plasma apolipoproteins can contribute to the clinical management of this neotropical primate species.

Methods: Lipid profile as well as A-1 and B apolipoprotein values were analyzed in 60 owl monkeys, studying their relationship with body biometry and the presence of cardiac alterations.

Results: Animals suspected of having heart disease did not show significant differences (p < .05) in terms of biometry or in relation to lipid profile and apolipoproteins A-1 and B values; however, higher values of LDL and ApoB and ApoB/ApoA-1 were observed in this group.

Conclusions: This study is the first to describe the lipid profile and apolipoprotein values in owl monkeys, and further work will be needed to better elucidate the worthiness of LDL, ApoB, and the ApoB/ApoA-1 ratio in this primate species.

Keywords: HDL; LDL; cholesterol; dyslipidemia; non-human primates; triglycerides.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Aotidae
  • Apolipoprotein A-I*
  • Apolipoproteins
  • Apolipoproteins B*

Substances

  • Apolipoprotein A-I
  • Apolipoproteins
  • Apolipoproteins B

Supplementary concepts

  • Aotus azarae