Intelligentization-oriented development is a fast-developing trend of technological revolution. It promotes the reconstruction of the industrial system of a region and affects its overall industrial competitiveness. This paper sets up a variety of models featuring intelligentization level and multi-dimensional industrial competitiveness, and collects data of 28 provinces and cities in China from 2003 to 2017 to test the influence of industrial intelligentization level on the industrial competitiveness of a region. The result reveals that: 1) In China's provincial jurisdictions, the higher the level of intelligentization is, the lower the overall level of industrial competitiveness and the lower the proportion of industry in the economic system will be. In regions where the facilities are highly intelligentialized, the production sectors tend to move to the less developed regions, and the growth effect of technological dividends is the focus. 2) Compared with the middle region and the Western region of China, the Eastern region, which is more developed with higher intelligentization level, has stronger ability in the research and development (R&D) of technologies, and the economic structure of the industry there tends to be stable, manifesting a strong growth potential.