Nutritional Status after Roux-En-Y (Rygb) and One Anastomosis Gastric Bypass (Oagb) at 6-Month Follow-Up: A Comparative Study

Paolo Gentileschi; Leandro Siragusa; Federica Alicata; Michela Campanelli; Chiara Bellantone; Tania Musca; Emanuela Bianciardi; Claudio Arcudi; Domenico Benavoli; Bruno Sensi

doi:10.3390/nu14142823

Nutritional Status after Roux-En-Y (Rygb) and One Anastomosis Gastric Bypass (Oagb) at 6-Month Follow-Up: A Comparative Study

Nutrients. 2022 Jul 9;14(14):2823. doi: 10.3390/nu14142823.

Authors

Paolo Gentileschi^{1

2}, Leandro Siragusa^{1

2}, Federica Alicata^{1

2}, Michela Campanelli^{1

2}, Chiara Bellantone³, Tania Musca³, Emanuela Bianciardi⁴, Claudio Arcudi^{1

2}, Domenico Benavoli^{1

2}, Bruno Sensi^{1

2}

Affiliations

¹ Department of Surgery, University of Rome Tor Vergata, 00133 Rome, Italy.
² Department of Bariatric and Metabolic Surgery, San Carlo di Nancy Hospital, 00165 Rome, Italy.
³ Department of Nutritional Sciences, San Carlo di Nancy Hospital, 00165 Rome, Italy.
⁴ Psychiatry Unit, Department of Medical Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.

Abstract

Introduction: Roux-en-Y gastric bypass (RYGB) and one anastomosis gastric bypass (OAGB) are two effective bariatric surgical procedures with positive outcomes in terms of weight loss, comorbidities remission, and adverse events profiles. OAGB seems to carry a higher risk of malnutrition, but existing data are controversial. The aim of this study is to objectively evaluate and compare malnutrition in patients undergoing RYGB and OAGB.

Methods: Retrospective monocentric study of obese patients undergoing RYGB or OAGB between the 15 September 2020 and the 31 May 2021. Nutritional status was assessed using the Controlling Nutritional Status (CONUT) score and compared between groups. The primary outcome was the mean CONUT score at 6 months. The secondary outcomes included the incidence of malnutrition, comorbidities, including hypertension, insulin resistance and type II diabetes mellitus, and weight loss.

Results: 78 patients were included: 30 underwent RYGB and 48 underwent OAGB. At 6-Month Follow-Up there was no difference between groups in the mean CONUT score nor in incidence of malnutrition. In both groups, the nutritional status significantly worsened 6 months after surgery (preoperative and postoperative score of 0.48 ± 0.9 and 1.38 ± 1.5; p = 0.0066 for RYGB and of 0.86 ± 1.5 and 1.45 ± 1.3; p = 0.0422 for OAGB). Type II Diabetes mellitus (DMII) and hypertension remission were significant in the OAGB group with a 100% relative remission in the DMII-OAGB group (p = 0.0265), and a 67% relative remission in the hypertension-OAGB group (p = 0.0031).

Conclusions: No difference in nutritional status has been detected between patients undergoing RYGB or OAGB at the 6-Month Follow-Up. Both procedures may have significant mal-absorptive effects leading to decline in nutritional status. OAGB may be more efficacious in inducing DMII and hypertension remission. Larger prospective studies dedicated specifically to nutritional status after gastric bypass are needed to confirm the impact of different bypass procedures on nutritional status.

Keywords: bariatric surgery; gastric bypass; metabolic surgery; nutrition; obesity.

MeSH terms

Diabetes Mellitus, Type 2* / complications
Gastric Bypass* / adverse effects
Gastric Bypass* / methods
Humans
Hypertension* / complications
Hypertension* / etiology
Malnutrition* / complications
Malnutrition* / etiology
Nutritional Status
Obesity, Morbid* / complications
Prospective Studies
Retrospective Studies
Weight Loss

Grants and funding

No funding was granted nor requested for this study.