Diagnostic and Therapeutic Challenges in a Patient with Radiation Retinopathy Complicated by Corticosteroid-Induced Central Serous Chorioretinopathy

Medicina (Kaunas). 2022 Jun 28;58(7):862. doi: 10.3390/medicina58070862.

Abstract

Central serous chorioretinopathy (CSC) is a common chorioretinal disorder. It has been postulated that impaired retinal pigment epithelium and hyperpermeability of the choriocapillaris may be involved in the development of CSC, but the exact pathomechanism has not been established. We report an unusual case of a middle-aged man who developed CSC after triamcinolone acetonide injection for macular edema. Edema developed as a late complication of radiation retinopathy after brachytherapy for childhood retinoblastoma. Steroid treatment is an important risk factor for CSC, but the underlying causative mechanisms have not been fully elucidated. It is important to increase the awareness of this link among clinicians who prescribe exogenous corticosteroids, irrespective of the route of administration.

Keywords: central serous chorioretinopathy; corticosteroids; macular edema; radiation retinopathy; retinoblastoma.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / adverse effects
  • Central Serous Chorioretinopathy* / chemically induced
  • Central Serous Chorioretinopathy* / complications
  • Child
  • Choroid
  • Glucocorticoids
  • Humans
  • Male
  • Middle Aged
  • Retinal Pigment Epithelium
  • Tomography, Optical Coherence

Substances

  • Adrenal Cortex Hormones
  • Glucocorticoids

Grants and funding

This research received no external funding.