Yeast Genomics and Its Applications in Biotechnological Processes: What Is Our Present and Near Future?

J Fungi (Basel). 2022 Jul 20;8(7):752. doi: 10.3390/jof8070752.

Abstract

Since molecular biology and advanced genetic techniques have become important tools in a variety of fields of interest, including taxonomy, identification, classification, possible production of substances and proteins, applications in pharmacology, medicine, and the food industry, there has been significant progress in studying the yeast genome and its potential applications. Because of this potential, as well as their manageability, safety, ease of cultivation, and reproduction, yeasts are now being extensively researched in order to evaluate a growing number of natural and sustainable applications to provide many benefits to humans. This review will describe what yeasts are, how they are classified, and attempt to provide a rapid overview of the many current and future applications of yeasts. The review will then discuss how yeasts-including those molecularly modified-are used to produce biofuels, proteins such as insulin, vaccines, probiotics, beverage preparations, and food additives and how yeasts could be used in environmental bioremediation and biocontrol for plant infections. This review does not delve into the issues raised during studies and research, but rather presents the positive outcomes that have enabled several industrial, clinical, and agricultural applications in the past and future, including the most recent on cow-free milk.

Keywords: Saccharomyces cerevisiae; biofuels; genetic manipulation; genomics; production of protein heterologues; vaccines; yeast diary products.

Publication types

  • Review

Grants and funding

This research received no external funding. The APC was funded by Vivian Tullio.