Intraarterial Therapies for the Management of Hepatocellular Carcinoma

Cancers (Basel). 2022 Jul 10;14(14):3351. doi: 10.3390/cancers14143351.

Abstract

Image-guided locoregional therapies play a crucial role in the management of patients with hepatocellular carcinoma (HCC). Transarterial therapies consist of a group of catheter-based treatments where embolic agents are delivered directly into the tumor via their supplying arteries. Some of the transarterial therapies available include bland embolization (TAE), transarterial chemoembolization (TACE), drug-eluting beads-transarterial chemoembolization (DEB-TACE), selective internal radioembolization therapy (SIRT), and hepatic artery infusion (HAI). This article provides a review of pre-procedural, intra-procedural, and post-procedural aspects of each therapy, along with a review of the literature. Newer embolotherapy options and future directions are also briefly discussed.

Keywords: bland embolization; drug-eluting beads–transarterial chemoembolization; hepatic artery infusion; hepatocellular carcinoma; selective internal radioembolization therapy; transarterial chemoembolization.

Publication types

  • Review