A Gut Feeling: Isolated Small Bowel Angioedema due to Angiotensin-Converting Enzyme Inhibitor

R I Med J (2013). 2022 Aug 1;105(6):28-31.

Abstract

Isolated angioedema of the small intestine is a rare adverse event in patients taking angiotensin-converting enzyme inhibitors. Here, we present a case of visceral angioedema in a 32-year-old woman who presented with left upper quadrant pain, nausea, vomiting, diarrhea, and characteristic radiographic signs of small bowel angio-edema, six months after starting lisinopril. Her symptoms improved within 48 hours of withholding the offending agent and with supportive care. We discuss the epidemiology, pathophysiology, diagnosis, and management of angiotensin-converting enzyme inhibitor- induced angioedema.

Keywords: ACE inhibitor; abdominal pain; visceral angioedema.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain
  • Adult
  • Angioedema* / chemically induced
  • Angioedema* / diagnostic imaging
  • Angiotensin-Converting Enzyme Inhibitors* / adverse effects
  • Antiviral Agents
  • Diarrhea
  • Female
  • Humans
  • Intestine, Small / diagnostic imaging

Substances

  • Angiotensin-Converting Enzyme Inhibitors
  • Antiviral Agents