Anisometropia is a condition of refractive interocular asymmetry and is usually referred only to as the clinically significant differences between the right and the left eye. According to studies conducted in different regions, the incidence of this common refractive abnormality ranges from 3.79% to 21.8%.
A difference of 1 diopter or more in spherical equivalent (SE) is usually reported to define this condition. Its clinical relevance comes from the fact that in a minority of individuals, this refractive disparity, anisometropia, is not corrected and leads to permanently low visual acuity (amblyopia) configuring, in the absence of other abnormalities, anisometropic amblyopia (24-37% of all amblyopias).
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